Research Lab: Davidson

Dr. J. Tyler Davidson is an Assistant Professor in the Department of Forensic Science at Sam Houston State University. His research interests are focused on forensic applications of mass spectrometry both to the worlds of seized drug analysis and toxicology. His research in the area of seized drug analysis is focused on the application of multivariate analysis for the classification of novel synthetic drugs and understanding characteristic fragmentation pathways. Dr. Davidson’s research in the world of toxicology involves structural elucidation with tandem mass spectrometry (MS/MS) and the application of ambient ionization techniques. His long-term research goals are to assist the seized drug and toxicological communities with the classification and identification of novel synthetic drugs through underlying fragmentation mechanisms, and to demonstrate the benefits of ambient ionization approaches to the analysis of toxicological samples.
Tyler Davidson

Specific research endeavors include:

  • Multivariate analysis for the classification of novel synthetic drugs
  • Forensic applications of ambient ionization mass spectrometry (AI-MS)
  • Exploration of alternative toxicological sample matrices
  • Structural elucidation with tandem mass spectrometry (MS/MS) and high-resolution mass spectrometry (HRMS)
  • Fundamental studies on the application of in-source CID to forensic science

Research Updates

  • In-Source CID manuscript accepted in the Journal of Mass Spectrometry

    November 2020

    Fragmentation Comparison

    This work provides a comparison between in-source CID and beam-type CID spectra of emerging synthetic drugs on the same Q-TOF instrument to better understand the fragmentation differences between these two fragmentation techniques, and to contribute to the scientific foundations of in-source CID. Available via DOI: 10.1002/jms.4679.

  • Dr. Davidson brings DART to SHSU

    October 2020

    DART Technology

    Direct analysis in real time (DART) is a rapid and noncontact ambient ionization source that allows for the direct testing of solid, liquid, or gas samples without the need for extensive sample preparation or extraction. SHSU now joins a growing network of academic, industrial, and government laboratories using DART-MS. DART-MS is a branch of Dr. Davidson’s ambient ionization mass spectrometry (AI-MS) research agenda here at SHSU.

  • Welcome to the Team - Ruby Liliedahl

    September 2020

    Ruby Liliedahl

    Ruby Liliedahl joins Dr. Davidson’s research group for her MS capstone project. Ruby is working on the differentiation of synthetic cathinone isomers using gas chromatography-electron ionization-mass spectrometry (GC-EI-MS) and multivariate analysis.

  • Welcome to the Team - Dr. Tyler Davidson

    August 2020

    Dr. Tyler Davidson

    Dr. Davidson joined the Department of Forensic Science at Sam Houston State University as an Assistant Professor.

  • 21st Annual FSF Emerging Forensic Scientist Award

    April 2020

    FSF Award

    J. Tyler Davidson was awarded the 21st Annual Forensic Science Foundation Emerging Forensic Scientist Award for his presentation titled, “On the Fragmentation Behavior of Fentanyl and Its Analogs in Electrospray Ionization-Tandem Mass Spectrometry (ESI-MS/MS)”.