Dr. Hinze

Dr. Meagan Hinze

Assistant Professor
Dr. Hinze photo
Contact Details

Office: CFS317J
Phone: 9362941060
Email: mehinze@shsu.edu


Butler University, B.Sc. Chemistry and German, 2009

Cornell University, M.S. 2012, Ph.D. 2015

University of Michigan (postdoc), 2015-2019

Research in the Hinze lab explores the biocatalytic activity of Baeyer-Villiger monooxygenases (BVMOs) with the aim to use the products toward the synthesis of bioactive compounds and diverse synthons. Students in the lab will develop various skills related to the areas of organic synthesis and chemical biology.

Independent publications: coming soon!
Mentored publications:

6. Zetzsche, L. E.#; Yazarians, J. A.#; Chakrabarty, S.; Hinze, M. E.; Murray, L. A. M.; Lukowski, A. L.; Joyce, L. A.; Narayan, A. R. H.* “Biocatalytic oxidative cross-coupling reactions for biaryl bond formation” Nature, 2022, 603, 79-85. DOI: 10.1038/s41586-021-04365-7

5. Lukowski, A. L.#; Mallik, L.#; Hinze, M. E.; Carlson, B. M.; Ellinwood, D. C.; Pyser, J. B.; Koutmos, M.; Narayan, A. R. H.* “Substrate promiscuity of a paralytic shellfish toxin amidinotransferase” ACS Chem. Biol. 2020, 15, 626-631. DOI: 10.1021/acschembio.9b00964

4. Lukowski, A. L.; Denomme, N.; Hinze, M. E.; Hall, S.; Isom, L. L.; Narayan, A. R. H.* “Biocatalytic Detoxification of Paralytic Shellfish Toxins” ACS Chem. Biol., 2019, 14, 941-948. DOI: 10.1021/acschembio.9b00123

3. Lukowski, A. L.; Ellinwood, D. C.; Hinze, M. E.; DeLuca, R. J.; Du Bois, J.; Hall, S.; Narayan, A. R. H.* “C-H hydroxylation in paralytic shellfish toxin biosynthesis” J. Am. Chem. Soc., 2018, 140, 11863-11869. DOI: 10.1021/jacs.8b08901

2. Chun, S. W.; Hinze, M. E.; Skiba, M. A.; Narayan, A. R. H.* “Chemistry of a unique polyketide-like synthase” J. Am. Chem. Soc., 2018, 140, 2430-2433. DOI: 10.1021/jacs.7b13297

1. Hinze, M. E.; Daughtry, J. L.; Lewis, C. A.* “Access to the Surugatoxin Alkaloids: Chemo-, Regio-, and Stereoselective Oxindole Annulation” J. Org. Chem., 2015, 80, 11258-11265. DOI: 10.1021/acs.joc.5b02053