1. If you are going on vacation or just have some time off, you can set an "Out of Office" message to be automatically sent in response to any messages you recieve. All you need to do is go to Tools > Out of Office Assistant.
2. After the assistant comes up (pictured on the right) you can choose whether you are "In the Office" or "Out of the Office". If you choose "Out of the Office" you can type an AutoReply message in the box below the radio buttons. This message will automatically be sent to anyone who you recieve an email from. You can also specify specific dates and times for the AutoReply to be activated.