IRB Application Walkthrough

Please take a moment to review the Introductory to CAYUSE IRB video some things have changed!


IRB Application Walkthrough

Welcome to the IRB Application Walkthrough. On this page you'll learn about the submission and review process, complete with links to the resources that you'll need every step of the way.

What You'll Need

Prior to beginning your IRB application, it is important to make sure that you have all of your papers in order, including all relevant supporting documentation and certifications from all required CITI training.

Tasks to complete

Complete your CITI Training

Final IRB submission and approval requires you to have completed research ethics training through CITI. Be sure to download a copy of your completion certificate for upload to the IRB form system.

Evaluate expedited review and exempt review options

Many research projects are eligible for expedited review, which allows researchers to have their IRB applications approved outside of a meeting of the full IRB. Some projects are also eligible for exempt review, which if approved allows research to be carried out without continuing review, unless a change in the project has occurred.

For more information about expedited review and exempt review, or for help in determining whether or not your research is eligible for either of these categories, please consult the IRB FAQ, or contact Sharla Miles.

After You Submit Your Application

What You'll Need

As you progress through your research project, you will need to ensure that you continue to meet institutional compliance standards. The IRB conducts continuing review of previously approved research on a periodic basis, which requires you to complete a form documenting any changes to your project, including changes related to personnel and funding. You may also expedite the continuing review process by updating the IRB when significant changes to your research occur by completing an amendment application. 

Tasks to complete

Reporting Adverse Events/Unanticipated Problems to the IRB

Federal regulations require PIs to promptly report any unanticipated problems involving risks to subjects or others to the IRB, appropriate institutional officials, and federal agencies. The IRB has the authority to suspend or terminate approval of research that is not being conducted in accordance with the IRB's requirements or that has been associated with unexpected serious harm to subjects. See Academic Policy Statement 140427 for further information.

Tasks to complete

Complete Your Final Report Form

Once your research project has been concluded according to the terms set forth in your IRB documentation, you will need to complete a final report form explaining the reasons for the conclusion of your project, as well as any additional issues that may need to be disclosed.